Marker Therapeutics, Inc.

+1 (713) 400-6400

3200 Southwest Fwy #2240 Phoenix Tower
Houston, TX 77027

© 2020 Marker Therapeutics, Inc.

A major leap forward in cell therapy

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Marker Therapeutics Reports Update from TACTOPS Trial with MultiTAA-Specific T Cell Therapy in Pancreatic Cancer at ASCO20

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The Company

We are a clinical-stage immuno-oncology company specializing in the development and commercialization of novel T cell-based immunotherapies and innovative peptide-based vaccines for the treatment of hematological malignancies and solid tumor indications. We developed our lead product candidates from our MultiTAA T cell technology, which is based on the selective expansion of non-engineered, tumor-specific T cells that recognize tumor-associated antigens, or TAAs, which are tumor targets, and then kill tumor cells expressing those targets.

Recognition

Marker Therapeutics, Inc. Congratulates Dr. James P. Allison for Receiving the 2018 Nobel Prize in Medicine or Physiology

Marker Therapeutics, Inc. Congratulates Dr. Padmanee Sharma for Receiving the William B. Coley Award for Distinguished Research in Tumor Immunology

At the 2019 Transplantation & Cellular Therapy Meetings of ASBMT and CIBMTR, Baylor College of Medicine Presented Data on Several Baylor Clinical Trials Employing Technology Exclusively Licensed to Marker

Marker Therapeutics Reports Interim Results of its MultiTAA-Specific T Cell Therapy in Patients with Pancreatic Adenocarcinoma at the 2020 American Society of Clinical Oncology (ASCO) Virtual Annual Meeting

Marker Therapeutics, Inc. today announced updated clinical results from an ongoing investigator-sponsored Phase 1 trial led by the Baylor College of Medicine, evaluating the Company’s MultiTAA-specific T cell therapy in patients with advanced or metastatic pancreatic adenocarcinoma. Data from a cohort of patients receiving MultiTAA-specific T cell therapy in combination with standard-of-care chemotherapy in the first-line setting (Arm A), were reviewed today by lead investigator, Brandon G. Smaglo, M.D., FACP, as part of a poster session during the 2020 American Society of Clinical Oncology (ASCO) Virtual Annual Meeting. ASCO is being held from Friday, May 29 through Sunday, May 31, 2020.

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Marker Therapeutics to Report Updated Results from Phase 1/2 Trial with MultiTAA-Specific T Cell Therapy in Patients with Pancreatic Adenocarcinoma at ASCO 2020 Annual Meeting

Marker Therapeutics, Inc. today announced that updated clinical data from an investigator-sponsored Phase 1/2 trial led by Baylor College of Medicine were selected for presentation during a poster session at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting.

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Clinical Studies

Marker has multiple clinical studies ongoing and planned for its multi-antigen T cell therapies. Target indications include acute myelogenous leukemia (AML), non-Hodgkin lymphoma (NHL), multiple myeloma (MM) and breast cancer.

Technology

Marker’s unique cell therapy platform is the first to successfully target multiple tumor-associated antigens simultaneously, without the need for genetic modification of patients’ T cells. The result is a remarkably robust and durable anti-tumor immune response and a manufacturing process that is simpler and less costly than today’s TCR and CAR-T therapy.

Pipeline

Marker has a deep pipeline of clinical-stage programs that leverage the company’s unique multi-TAA cell therapy platform, addressing multiple hematologic malignancies and solid tumors. The company is also advancing its novel peptide vaccine in breast and ovarian cancer.

Management Team

Marker is led by an executive management team specialized in cancer immunotherapy, bringing together extensive corporate, clinical, translational and medical experience. With its world-class scientific advisors, Marker is well positioned to advance its science-based approach to transforming the cell therapy landscape.

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© 2020 Marker Therapeutics, Inc.